Novelty

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Chapter 1 endnote 42, from How Emotions are Made: The Secret Life of the Brain by Lisa Feldman Barrett.
Some context is:

In 2008, my lab along with neurologist Chris Wright demonstrated why the amygdala increases in activity in response to the basic emotion fear faces. The activity increases in response to any face ​— ​whether fearful or neutral ​— ​ as long as it is novel (i.e., the test subjects have not seen it before).[1]

This effect was first observed by Dubois et al. (1999).[2][3]

For other scientific papers on the amygdala and its relation to novelty, see these references.[4][5][6][7][8][9][10]


Notes on the Notes

  1. Wright, C. I., Negreira, A., Gold., A. L., Britton, J. C., Williams, D., & Barrett, L. F. (2008). Neural correlates of novelty and face-age effects in young and elderly adults.  Neuroimage, 42, 956-968. 
  2. Dubois, S., Rossion, B., Schiltz, C., Bodart, J.M., Michel, C., Bruyer, R., Crommelinck, M., 1999. Effect of familiarity on the processing of human faces. Neuroimage 9, 278–289.
  3. Wilson, F. A. & Rolls, E. T. (1993). The effects of stimulus novelty and familiarity on neuronal activity in the amygdala of monkeys performing recognition memory tasks. Exp Brain Res, 93 (3), 367-82.
  4. Schwartz, C.E.,Wright, C.I., Shin, L.M., Kagan, J., Whalen, P.J., McMullin, K.G., Rauch, S.L., 2003. Differential amygdalar response to novel versus newly familiar neutral faces: a functional MRI probe developed for studying inhibited temperament. Biol. Psychiatry. 53, 854–862.
  5. Wright, C.I., Martis, B., Schwartz, C.E., Shin, L.M., Fischer, H.H., McMullin, K., Rauch, S.L., 2003. Novelty responses and differential effects of order in the amygdala, substantia innominata, and inferior temporal cortex. Neuroimage 18, 660–669.
  6. Weierich, M. R., Wright, C. I., Negreira, A., Dickerson, B. C., & Barrett, L. F. (2010). Novelty as a dimension of the affective brain.  Neuroimage, 49, 2871-2878    
  7. Blackford et al. (2010). A unique role for the human amygdala in novelty detection. Neuroimage, 50, 1188-93.
  8. Moriguchi, Y, Negreira, A., Weierich, M., Dautoff, R., Dickerson, B. C., Wright, C. I., & Barrett, L. F .  (2011). Differential hemodynamic response in affective circuitry with aging:  An fMRI study of novelty, valence, and arousal. Journal of Cognitive Neuroscience, 23, 1027-41.
  9. Mason et al. (2006). Amygdalectomy and responsiveness to novelty in rhesus monkeys (Macaca mulatta): generality and individual consistency of effects. Emotion, 6(1), 73-81.
  10. Balderston et al. (2011). The human amygdala plays a stimulus specific role in the detection of novelty. Neuroimage, 55(4), 1889-98.