LSD and prediction

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Chapter 4 endnote 19, from How Emotions are Made: The Secret Life of the Brain by Lisa Feldman Barrett.
Some context is:

Figure 4-3: A variety of mental phenomena can be understood as a combination of prediction and sensory input [including LSD trips].

People who take the drug LSD may experience the world in fantastical and mystical ways because their perceptions are dominated by prediction error rather than prediction. LSD appears to impair the function of intrinsic networks,[1] particularly those responsible for initiating predictions,[2][3] which would change the balance of prediction and prediction error in the brain.

Notes on the Notes

  1. Carhart-Harris, Robin L., Suresh Muthukumaraswamy, Leor Rosemana, Mendel Kaelena, Wouter Droog, et al. 2016. “Neural Correlates of the LSD Experience Revealed by Multimodal Neuroimaging.” Proceedings of the National Academy of Sciences 113 (7): 4853–4858.
  2. Barrett, Lisa Feldman, and W. Kyle Simmons. 2015. “Interoceptive Predictions in the Brain.” Nature Reviews Neuroscience 16 (7): 419–429.
  3. Chanes, Lorena, and Lisa Feldman Barrett. 2016. “Redefining the Role of Limbic Areas in Cortical Processing.” Trends in Cognitive Sciences 20 (2): 96–106.