Inflammation changes brain structure

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Chapter 10 endnote 5, from How Emotions are Made: The Secret Life of the Brain by Lisa Feldman Barrett.
Some context is:

Inflammation in the brain causes changes in brain structure, particularly within your interoceptive network...

Inflammation is linked to atrophy in prefrontal cortex and the hippocampus,[1] but not in the amygdala which instead shows hypertrophy.[2][3][4]

See also

Notes on the Notes

  1. Soskin, David P., Clair Cassiello, Oren Isacoff, and Maurizio Fava. 2012. “The Inflammatory Hypothesis of Depression.” Focus 10 (4): 413–421.
  2. Ganzel, Barbara L., Pamela A. Morris, and Elaine Wethington. 2010. “Allostasis and the Human Brain: Integrating Models of Stress from the Social and Life Sciences.” Psychological Review 117 (1): 134–174.
  3. McEwen, Bruce S., and Peter J. Gianaros. 2011. “Stress- and Allostasis-Induced Brain Plasticity.” Annual Review of Medicine 62: 431–445.
  4. McEwen, Bruce S., Nicole P. Bowles, Jason D. Gray, Matthew N. Hill, Richard G. Hunter, Ilia N. Karatsoreos, and Carla Nasca. 2015. “Mechanisms of Stress in the Brain.” Nature Neuroscience 18 (10): 1353–1363.